Roche is a Swiss healthcare company founded in 1896 by Fritz Hoffmann-La Roche in Basel, Switzerland, where it remains headquartered. It is one of the largest pharmaceutical companies in the world and the global leader in in-vitro diagnostics, operating through two divisions: Pharmaceuticals and Diagnostics. Roche built its modern pharmaceutical business largely around biotechnology, acquiring a majority stake in Genentech in 1990 and full ownership in 2009, and holding a majority of Japan's Chugai Pharmaceutical. The company is historically the world leader in oncology, with medicines including Herceptin, Avastin, and Rituxan, and newer therapies such as Tecentriq, Ocrevus for multiple sclerosis, Hemlibra for hemophilia A, and Vabysmo for retinal disease. Its Diagnostics division supplies laboratory analyzers, molecular and tissue diagnostics, and point-of-care tests used by hospitals and labs worldwide, and played a major role in COVID-19 testing. Roche also markets the Accu-Chek line of blood glucose monitoring products for diabetes care. The group employs around 100,000 people, sells in over 100 countries, and reports annual revenue near 60 billion Swiss francs. Founding family descendants still hold a controlling interest in the voting shares, making Roche one of the largest family-influenced companies in the world. Multiple Roche medicines appear on the World Health Organization's Model List of Essential Medicines, and the company consistently ranks among the industry's largest investors in research and development.
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